4th ISFMS—Biochemistry, Molecular Biology and Druggability of Proteins
4th ISFMS—Biochemistry, Molecular Biology and Druggability of Proteins
Part of the International Symposium on Frontiers in Molecular Science series
24th June 2022
1st July 2022
11th July 2022
29th July 2022
20th July 2022
Protein Chemistry, Proteins As Drug Target, Protein Structure and Function
Due to the many requests from several attendees, the deadline for abstract submission to oral and poster presentations has been extended until 24 June 2022.
Don't miss this opportunity to participate on ISFMS2022!
Welcome from the Chairs
We look forward to seeing you in Florence.
Claudiu T. Supuran, Paola Gratteri, Silvia Selleri & Clemente Capasso
Follow the conversation on Twitter with #ISFMS2022
Download the conference poster here.
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Conference Secretariat
Reyna LiAna Sanchis
Email: [email protected]
Sponsoring Opportunities
For information regarding sponsorship and exhibition opportunities, please contact:
E-Mail: [email protected]
Conference Chairs
Prof. Dr. Claudiu T. Supuran
University of Florence Neurofarba Department, Firenze, Italy
Prof. Dr. Paola Gratteri
University of Florence Neurofarba Department, Firenze, Italy
Prof. Dr. Silvia Selleri
University of Florence Neurofarba Department, Firenze, Italy
Dr. Clemente Capasso
National Research Council, Napoli, Italy
Conference Committee
Prof. Dr. Gyula Batta
University of Debrecen, Debrecen, Hungary
Prof. Dr. Cheorl-Ho Kim
Department of Biological Sciences, College of Science, Sungkyunkwan University, Korea
Prof. Dr. Maria Ruzzene
Department of Biomedical Sciences, University of Padova, Italy
Prof. Dr. Barbara Jachimska
Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Poland
www.researchgate.net/profile/Barbara_Jachimska
Prof. Dr. Carlos Salgueiro
NOVA School of Science and Technology, NOVA University Lisbon, Portugal
Prof. Dr. Ryszard Lobinski
French National Center for Scientific Research (CNRS), France
Prof. Dr. Tiziana Marino
Dipartimento di Chimica e Tecnologie Chimiche, Presidente SCI Sezione Calabria, Italy
Dr. Anindita Das
Division of Cardiology, Pauley Heart Center, Department of Internal Medicine, Virginia Commonwealth University, USA
Prof. Dr. Nikolai Barlev
Institute of Cytology of Russian Academy of sciences, Russia
Keynote Speakers
Prof. Dr. Shoukat Dedhar
Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada
Hypoxia and Ferroptosis: Co-targeting Approaches in Cancer
Dr Shoukat Dedhar is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver. He is a Fellow of the Royal Society of Canada. Known for his seminal discovery of Integrin-Linked Kinase (ILK), an essential protein involved in the regulation of cytoskeletal organization and signal transduction, he has also made significant contributions in the field of tumour microenvironment/hypoxia, and co-developed a new inhibitor of CAIX, currently in clinical trials.
Prof. Dr. Binghe Wang
Department of Chemistry, and Center for Diagnostics and Therapeutic, Georgia State University, Atlanta, GA, USA
Dr. Binghe Wang is Regents’ Professor of Chemistry, Georgia Research Alliance Eminent Scholar in Drug Discovery, and Director of Center for Diagnostics and Therapeutics at Georgia State University. Dr. Wang obtained his B.S. degree in medicinal chemistry from Beijing Medical College in 1982, and his Ph.D. degree in medicinal chemistry from the University of Kansas in 1991. He served at the University of Oklahoma and at North Carolina State University before he was recruited to a Georgia Research Alliance Eminent Scholar position at Georgia State University, where he also served as Chair of the Department of Chemistry, Associate Dean for Natural and Computational Sciences, Associate Dean for Research, Graduate Studies, and Innovation, and Interim Dean of the College of Arts and Sciences. Dr. Wang’s research covers drug design, drug delivery, chemosensing, chemical biology, and organic chemistry. He has published over 320 scientific papers and given over 220 invited lectures worldwide. He served for 20 years as the Editor-in-Chief of a high-impact journal, Medicinal Research Reviews between 2000-2019, and founding serial editor of “Wiley Series in Drug Discovery and Development,” which has published over 20 volumes. He has edited books in areas including drug design, drug delivery, pharmaceutical profiling, chemosensing, carbohydrate recognition, and therapeutic applications of carbon monoxide. Internationally, Dr. Wang has served on many panels and editorial boards including his 7-year membership on the Synthetic and Biological Chemistry-A Study Section (SBC-A) at the NIH. He has also led or participated in the organization, and/or presided over more than 40 international symposia and conferences.
Prof. Dr. Marianna A. Patrauchan
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, USA
Molecular pillars of calcium signaling in a bacterial pathogen, Pseudomonas aeruginosa.
Dr. Patrauchan is a Professor of Microbiology in the Department of Microbiology and Molecular Genetics at Oklahoma State University. She holds a PhD in Microbiology (National Academy of Sciences, Ukraine) and received postdoctoral training in molecular microbiology (Michigan State University, Montana State University, and University of British Columbia). Dr. Patrauchan’s research focuses on understanding calcium signaling in a human pathogen Pseudomonas aeruginosa.
Prof. Dr. William Donald
School of Chemistry, University of New South Wales (UNSW) Australia, Sydney, Australia
Multiplexed screening of thousands of natural products for protein-ligand binding in native mass spectrometry
William A. Donald is an Associate Professor, Australian Research Council Future Fellow, and Scientia Fellow in the School of Chemistry at the University of New South Wales, Sydney. He received his B.Sc. degree in Chemistry from Seattle University in 2005 and a Ph.D. from the University of California, Berkeley in 2010. After a research fellowship at the University of Melbourne, he joined the School of Chemistry at the University of New South Wales in 2013. He is currently an associate editor for the Journal of Enzyme Inhibition and Medicinal Chemistry. His research interests include mass spectrometry and ion chemistry, with an emphasis on developing and applying instrumentation and methods to problems of interest in biochemistry.
Prof. Dr. Jean-Yves WINUM
IBMM - Pôle Chimie Balard Recherche, University of Montpellier, Montpellier, France
Innovative approaches targeting carbonic anhydrases: an update.
Jean-Yves Winum received his PhD in chemistry from the University of Montpellier (France) in 1998. He then worked as a postdoctoral fellow in the Chemistry department of Georgetown University (Washington, DC) and of the University of Geneva (Switzerland). In 1999, he joined the University of Montpellier, where he is now Full Professor. His research interests are focused on organic/medicinal chemistry of metalloenzyme inhibitors. He published more than 190 articles (h-index 44) in this field.
Prof. Dr. Ionel Mangalagiu
Faculty of Chemistry, “Alexandru Ioan Cuza” University of Iasi, Iasi, Romania
Dual- or Multi- Trageting Azaheterocycles: Next Generation of Drugs in Medicinal Chemistry.
Dr. Mangalagiu is a professor of organic and medicinal chemistry and Vice-Rector with research at “Alexandru Ioan Cuza” University of Iasi, Romania. He has nearly 30 years of experience in the research, focused in the area of Heterocycles Compounds. He has over 200 papers, 15 patents, 3 international chapter books, etc. He was Visiting Professor and/or invited speaker to prestigious foreign universities (Ludwig Maximilianus University Munchen, Technische Universität Braunschweig, University of Florence, Universite D’Angers), awarded with numerous prizes and honours: DAAD and NATO award, “Costin D. Nenitescu Medal” (Romanian Society of Chemistry), “Al.I.Cuza University Award in Research”, Special Award of Croatian Association of Inventors, etc. More information’s to: http://teclu.chem.uaic.ro/mangalagiu; ORCID number 0000-0002-4632-5076
Prof. Dr. Vladimir N. Uversky
Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, USA
Prof. Dr. Giuseppina De Simone
Biostructure and Bioimaging Institute-CNR, Naples, Italy"
Prof. Dr. Daniel P. Flaherty
Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, USA
Bacterial carbonic anhydrase inhibitors for the treatment of drug resistant bacteria: A classical drug scaffold gets a new purpose
Dr. Flaherty received his Ph.D. in pharmaceutical sciences at the University of Nebraska Medical Center. He then moved to the University of Kansas and joined an NIH sponsored medicinal chemistry lab under the direction of Dr. Jeffrey Aubé as a post-doctoral researcher and later as a research track faculty. He is now an assistant professor of medicinal chemistry in the Department of Medicinal Chemistry and Molecular Pharmacology at Purdue University focused on drug design for new antibiotics.
Dr. Łukasz Jaremko
Molecular Diagnostics and Drug Discovery (MD3) Group, Smart-Health Initiative (SHI), Red Sea Research Center (RSRC), Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Kingdom of Saudi Arabia
Elevated protein dynamics and druggability
Research in Professor Łukasz Jaremko's Molecular Diagnostics and Drug Discovery (MD3) group focuses on atomic-level insight into essential and topical questions from biochemistry and medicine, such as, e.g., the primary molecular bases of cancer, including leukaemia and lung cancer (Nature, 2021). The team is actively working in the field of targeted drug design and discovery, using structure-dynamics analysis to search for small molecules (ligands) that interact specifically with the disease-associated proteins. Identified lead compounds are then engineered to increase their binding and, thus therapeutic potency against cancer (Nature Chem Biol, 2021). Biomolecular nuclear magnetic resonance (NMR) spectroscopy is the crucial experimental technique used and refined (J Chem Phys B, 2015; Angewandte Chem, 2016; J Biomol NMR, 2018, 2020) to tackle challenging macromolecular assemblies (Nature Chem Biol, 2013, 2021; Science, 2014; Nature Communications, 2016, 2017; Nucleic Acids Res, 2019; Am J Hum Genetics, 2019; Chemical Science, 2020; eLife, 2021; Nature 2021; Mol. Cell 2021). These NMR-based structural studies are then combined with molecular and enzymatic assays as well as other state-of-the-art biophysical techniques such as X-ray crystallography, electron microscopy, circular dichroism and molecular dynamics simulations to get further insights into the complex biological systems essential for human health. Professor Łukasz Jaremko has published over 90 peer-reviewed papers in international journals covering original research of both methods development and application to address and monitor the pivotal biological, biomedical and environmental phenomena.
Registration
The registration fee includes attendance of all conference sessions, morning/afternoon coffee breaks and lunches, conference bag and program book.
Participation to the conference is considered final only once the registration fees have been paid. The number of participants is limited: once the number of paid registrations reaches the maximum number of participants, unpaid registrations will be cancelled.
Please note that, in order to finalize the scientific program in due time, at least one registration by anyone of the authors, denoted as Covering Author, is required to cover the presentation and publication of any accepted abstract. Covering Author registration deadline is 20 July 2022. Your abstract will be withdrawn if your registration is not complete by this date.
Authors with multiple contributions: Please note that one author registration will cover only ONE accepted contribution. Authors presenting more than 1 contribution during the event will be charged 25 euro per additional abstract (e.g., 1 author with 2 abstracts: registration fee + 25 euro; 2 authors with 3 abstracts: 2 registration fees + 25 euro; etc.)
Authors and reviewers of IJMS: Please note that the authors and reviewers of IJMS from the last 5 years will receive a 15% discount on the registration fees. This discount is not immediate, so you need to add the code AUT/REV-ISFMS2022 during your registration process. For any question or doubt, please send us an email to [email protected].
Certificate of Attendance: After the event, the participants of ISFMS2022 will be able to download an electronic Certificate of Attendance by log-in at their Sciforum personal account. Once you're logged-in, go to your profile and click on 'My certificates'. A list of all Sciforum events you've attended is available and you simply have to click on "Download" next to the correct event.
Conference Dinner: A Gala Dinner will be served on Friday, 9 September. Please note that the conference fee does not include this social event. Therefore, if you plan to attend the dinner, please make sure you select this extra when registering to the conference (Price per person: will be announced soon). Other social/networking events to be announced soon!
| Early | Regular | Late | Supported documents | |
|---|---|---|---|---|
| Student | 250.00 EUR | 350.00 EUR | 450.00 EUR |
Scanned copy or photograph of your current student ID is required. |
| Editorial Board Members/Guest Editors of IJMS | 350.00 EUR | 450.00 EUR | 550.00 EUR | |
| Post-Docs, PIs & Senior Scientists | 450.00 EUR | 550.00 EUR | 650.00 EUR | |
| Commercial | 700.00 EUR | 800.00 EUR | 900.00 EUR | |
| Waived Fees: Invited Speakers and MDPI Guests | Free | Free | Free |
Cancellation policy
Cancellation of paid registration is possible under the terms listed below:
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> 2 months before the conference |
Full refund but 60 EUR are retained for administration |
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> 1 month before the conference |
Refund 50% of the applying fees |
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> 2 weeks before the conference |
Refund 25% of the applying fees |
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< 2 weeks before the conference |
No refund |
Disclaimer
In the unlikely event that MDPI shall deem it necessary to cancel the conference, all pre-paid registration fees will be reimbursed. MDPI shall not be liable for reimbursing the cost of travel or accommodation arrangements made by individual delegates.
Photographs and/or video will be taken during the conference
By taking part in this event you grant the event organizers full rights to use the images resulting from the photography/video filming, and any reproductions or adaptations of the images for fundraising, publicity or other purposes to help achieve the conference’s aims. This might include (but is not limited to), the right to use them in their printed and online publicity, social media, press releases and funding applications.
Payment methods
Wire transfer, Credit card
Instructions for Authors
The "4th ISFMS — Biochemistry, Molecular Biology and Druggability of Proteins" will accept abstracts only.
The accepted abstracts will be available online on Sciforum.net during and after the conference. Moreover, participants will have the opportunity to contribute with a full manuscript to the special issue "Biochemistry, Molecular Biology and Druggability of Proteins" in the journal IJMS.
To present your research at the event
- Create an account on Sciforum if you do not have one, then click on ‘New Submission’ on the upper-right corner of the window, or by clicking on ‘Submit Abstract’ at the top of this webpage.
- Indicate what thematic area is best suited for your research.
- Submit an abstract in English - the word limits are: minimum 150 words and maximum 300 words.
- The deadline to submit your abstract is 24 June 2022. You will be notified by 1 July 2022 about the acceptance for poster presentation.
- Upon submission, you can select if you wish to also be considered for oral presentation. Following assessment by the Chairs, you will be notified by 1 July 2022 in a separate email whether your contribution has been accepted for oral presentation.
- Please note that, in order to finalize the scientific program in due time, at least one registration by any of the authors, denoted as Covering Author, is required to cover the presentation and publication of any accepted abstract. Covering Author registration deadline is 20 July 2022. Your abstract will be withdrawn if your registration is not complete by this date.
Poster Information
Maximum poster size limited to 90 × 140cm, vertical orientation preferred. Please print your poster prior to the conference.
A plan of the poster session will be circulated later on.
Publication Opportunities
- All accepted abstracts will be available online in Open Access form on Sciforum.net.
- Participants of this conference are cordially invited to contribute with a full manuscript to our Special Issue "Biochemistry, Molecular Biology and Druggability of Proteins" in the journal IJMS.
- The submission deadline for this special issue is 28 February 2023. Conference participants will be granted a 15% discount on the publication fees. Please note that no other institutional discounts will be applicable, except from reviewers’ discount vouchers.
- IJMS is indexed by the Science Citation Index Expanded (Web of Science), MEDLINE (PubMed), and other databases, and has an Impact Factor of 5.923 (2020).
Venue, Travel and Accommodation
Florence
Florence is a city in central Italy and the capital of the Tuscany region. During the Middle Ages, Florence was a centre of European trade and finance, and one of the wealthiest cities of that era.
The city attracts millions of tourists each year, and UNESCO declared the Historic Center of Florence a World Heritage Site in 1982. The city is noted for its culture, Renaissance art and architecture and monuments. The city also boasts numerous museums and art galleries, such as the Uffizi Gallery and the Palazzo Pitti, and still influences the fields of art, culture and politics to this day. Due to Florence's artistic and architectural heritage, Forbes has ranked it as one of the most beautiful cities in the world.
For more information visit http://www.firenzeturismo.it/en/.
Venue
The conference will take place in the biomedical campus of University of Florence, Viale G. Morgagni.
Best way to travel here
Accommodation
There are huge numbers of tourists visiting Florence and Tuscany each year, in every season. For this reason, the accommodation should be booked in advance. There is a large number of hotels, B&Bs, Airbnbs or apartments which can be booked online by using booking.com or similar services. The best location to choose would be around the Santa Maria Novella train station or city centre, where the journey to the conference site will take roughly 15 minutes.
Beware of Unauthorized Registration and Hotel Solicitations
Note that Sciforum is the only official registration platform to register to ISFMS2022, and that we are not associated with any hotel agency. While other hotel resellers and travel agencies may contact you with offers for your trip, they are not endorsed by or affiliated with ISFMS2022 or Sciforum. Beware that entering into financial agreements with non-endorsed companies can have costly consequences.
Event Awards
The Sponsor, IJMS, offers two Best Posters Awards and one Best Oral Presentation award to our conference participants, which will be announced during the Award Ceremony on the last day of the conference.
The Awards
The two Best Posters will be selected by all conference attendees through secret vote.
The Best Oral Presentation will be selected by the Scientific Committee after evaluation of all selected talks presented during the conference
Sponsors and Partners
Sponsors and Partners
Sponsoring opportunities
If you are interested in knowing the sponsorship options for ISFMS2022 please look at our Sponsorship form.
For sponsorship and exhibition opportunities, please do not hesitate to contact us for more information.
Organizers
Sponsors
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