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4th ISFMS—Biochemistry, Molecular Biology and Druggability of Proteins

Part of the International Symposium on Frontiers in Molecular Science series
6–9 Sep 2022, Florence, Italy
Abstract Submission
24th June 2022
Acceptance Notification
1st July 2022
Early Bird Registration
11th July 2022
Late Registration
29th July 2022
Covering Author Registration
20th July 2022

Protein Chemistry, Proteins As Drug Target, Protein Structure and Function
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Due to the many requests from several attendees, the deadline for abstract submission to oral and poster presentations has been extended until 24 June 2022.
Don't miss this opportunity to participate on ISFMS2022!

Welcome from the Chairs

Dear Colleagues,

We would like to invite you to The 4th ISFMS: Biochemistry, Molecular Biology and Druggability of Proteins, which will be held in the wonderful city of Florence, Italy, in the period September 6–9, 2022. The conference will be hosted at the University of Florence, in the biomedical campus nearby the main city hospital, which is easily accessible from the airport, train station or city center. Apart the high quality science which will be presented during the event, our fantastic location will afford the possibility to visit the city in which Leonardo da Vinci, Michelangelo and Galileo Galilei (to mention just a few personalities) lived and created some of their unique artistic and scientific masterpieces. The friendly and peaceful atmosphere of our city will surely favor nice scientific interactions and the possibility to establish interesting contacts with scientists from all over the world in a collaborative manner.

We look forward to seeing you in Florence.

Claudiu T. Supuran, Paola Gratteri, Silvia Selleri & Clemente Capasso

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Download the conference poster here.

Sponsored By

Media Partner

Conference Secretariat

Reyna Li
Ana Sanchis

Sponsoring Opportunities

For information regarding sponsorship and exhibition opportunities, please contact:
E-Mail:

Conference Chairs

Prof. Dr. Claudiu T. Supuran

University of Florence Neurofarba Department, Firenze, Italy

Prof. Dr. Paola Gratteri

University of Florence Neurofarba Department, Firenze, Italy

Prof. Dr. Silvia Selleri

University of Florence Neurofarba Department, Firenze, Italy

Dr. Clemente Capasso

National Research Council, Napoli, Italy

Conference Committee

Prof. Dr. Gyula Batta

University of Debrecen, Debrecen, Hungary

DETAILS

Prof. Dr. Cheorl-Ho Kim

Department of Biological Sciences, College of Science, Sungkyunkwan University, Korea

DETAILS

Prof. Dr. Maria Ruzzene

Department of Biomedical Sciences, University of Padova, Italy

DETAILS

Prof. Dr. Barbara Jachimska

Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Poland

DETAILS
Bio
www.researchgate.net/profile/Barbara_Jachimska

Prof. Dr. Carlos Salgueiro

NOVA School of Science and Technology, NOVA University Lisbon, Portugal

DETAILS

Prof. Dr. Ryszard Lobinski

French National Center for Scientific Research (CNRS), France

DETAILS

Prof. Dr. Tiziana Marino

Dipartimento di Chimica e Tecnologie Chimiche, Presidente SCI Sezione Calabria, Italy

DETAILS

Dr. Anindita Das

Division of Cardiology, Pauley Heart Center, Department of Internal Medicine, Virginia Commonwealth University, USA

DETAILS

Prof. Dr. Nikolai Barlev

Institute of Cytology of Russian Academy of sciences, Russia

DETAILS

Keynote Speakers

Prof. Dr. Shoukat Dedhar

Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada

DETAILS
Talk
Hypoxia and Ferroptosis: Co-targeting Approaches in Cancer
Bio
Dr Shoukat Dedhar is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver. He is a Fellow of the Royal Society of Canada. Known for his seminal discovery of Integrin-Linked Kinase (ILK), an essential protein involved in the regulation of cytoskeletal organization and signal transduction, he has also made significant contributions in the field of tumour microenvironment/hypoxia, and co-developed a new inhibitor of CAIX, currently in clinical trials.

Prof. Dr. Binghe Wang

Department of Chemistry, and Center for Diagnostics and Therapeutic, Georgia State University, Atlanta, GA, USA

DETAILS
Bio
Dr. Binghe Wang is Regents’ Professor of Chemistry, Georgia Research Alliance Eminent Scholar in Drug Discovery, and Director of Center for Diagnostics and Therapeutics at Georgia State University. Dr. Wang obtained his B.S. degree in medicinal chemistry from Beijing Medical College in 1982, and his Ph.D. degree in medicinal chemistry from the University of Kansas in 1991. He served at the University of Oklahoma and at North Carolina State University before he was recruited to a Georgia Research Alliance Eminent Scholar position at Georgia State University, where he also served as Chair of the Department of Chemistry, Associate Dean for Natural and Computational Sciences, Associate Dean for Research, Graduate Studies, and Innovation, and Interim Dean of the College of Arts and Sciences. Dr. Wang’s research covers drug design, drug delivery, chemosensing, chemical biology, and organic chemistry. He has published over 320 scientific papers and given over 220 invited lectures worldwide. He served for 20 years as the Editor-in-Chief of a high-impact journal, Medicinal Research Reviews between 2000-2019, and founding serial editor of “Wiley Series in Drug Discovery and Development,” which has published over 20 volumes. He has edited books in areas including drug design, drug delivery, pharmaceutical profiling, chemosensing, carbohydrate recognition, and therapeutic applications of carbon monoxide. Internationally, Dr. Wang has served on many panels and editorial boards including his 7-year membership on the Synthetic and Biological Chemistry-A Study Section (SBC-A) at the NIH. He has also led or participated in the organization, and/or presided over more than 40 international symposia and conferences.

Prof. Dr. Marianna A. Patrauchan

Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, USA

DETAILS
Talk
Molecular pillars of calcium signaling in a bacterial pathogen, Pseudomonas aeruginosa.
Bio
Dr. Patrauchan is a Professor of Microbiology in the Department of Microbiology and Molecular Genetics at Oklahoma State University. She holds a PhD in Microbiology (National Academy of Sciences, Ukraine) and received postdoctoral training in molecular microbiology (Michigan State University, Montana State University, and University of British Columbia). Dr. Patrauchan’s research focuses on understanding calcium signaling in a human pathogen Pseudomonas aeruginosa.

Prof. Dr. William Donald

School of Chemistry, University of New South Wales (UNSW) Australia, Sydney, Australia

DETAILS
Talk
Multiplexed screening of thousands of natural products for protein-ligand binding in native mass spectrometry
Bio
William A. Donald is an Associate Professor, Australian Research Council Future Fellow, and Scientia Fellow in the School of Chemistry at the University of New South Wales, Sydney. He received his B.Sc. degree in Chemistry from Seattle University in 2005 and a Ph.D. from the University of California, Berkeley in 2010. After a research fellowship at the University of Melbourne, he joined the School of Chemistry at the University of New South Wales in 2013. He is currently an associate editor for the Journal of Enzyme Inhibition and Medicinal Chemistry. His research interests include mass spectrometry and ion chemistry, with an emphasis on developing and applying instrumentation and methods to problems of interest in biochemistry.

Prof. Dr. Jean-Yves WINUM

IBMM - Pôle Chimie Balard Recherche, University of Montpellier, Montpellier, France

DETAILS
Talk
Innovative approaches targeting carbonic anhydrases: an update.
Bio
Jean-Yves Winum received his PhD in chemistry from the University of Montpellier (France) in 1998. He then worked as a postdoctoral fellow in the Chemistry department of Georgetown University (Washington, DC) and of the University of Geneva (Switzerland). In 1999, he joined the University of Montpellier, where he is now Full Professor. His research interests are focused on organic/medicinal chemistry of metalloenzyme inhibitors. He published more than 190 articles (h-index 44) in this field.

Prof. Dr. Ionel Mangalagiu

Faculty of Chemistry, “Alexandru Ioan Cuza” University of Iasi, Iasi, Romania

DETAILS
Talk
Dual- or Multi- Trageting Azaheterocycles: Next Generation of Drugs in Medicinal Chemistry.
Bio
Dr. Mangalagiu is a professor of organic and medicinal chemistry and Vice-Rector with research at “Alexandru Ioan Cuza” University of Iasi, Romania. He has nearly 30 years of experience in the research, focused in the area of Heterocycles Compounds. He has over 200 papers, 15 patents, 3 international chapter books, etc. He was Visiting Professor and/or invited speaker to prestigious foreign universities (Ludwig Maximilianus University Munchen, Technische Universität Braunschweig, University of Florence, Universite D’Angers), awarded with numerous prizes and honours: DAAD and NATO award, “Costin D. Nenitescu Medal” (Romanian Society of Chemistry), “Al.I.Cuza University Award in Research”, Special Award of Croatian Association of Inventors, etc. More information’s to: http://teclu.chem.uaic.ro/mangalagiu; ORCID number 0000-0002-4632-5076

Prof. Dr. Vladimir N. Uversky

Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, USA

Prof. Dr. Giuseppina De Simone

Biostructure and Bioimaging Institute-CNR, Naples, Italy"

Prof. Dr. Daniel P. Flaherty

Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, USA

DETAILS
Talk
Bacterial carbonic anhydrase inhibitors for the treatment of drug resistant bacteria: A classical drug scaffold gets a new purpose
Bio
Dr. Flaherty received his Ph.D. in pharmaceutical sciences at the University of Nebraska Medical Center. He then moved to the University of Kansas and joined an NIH sponsored medicinal chemistry lab under the direction of Dr. Jeffrey Aubé as a post-doctoral researcher and later as a research track faculty. He is now an assistant professor of medicinal chemistry in the Department of Medicinal Chemistry and Molecular Pharmacology at Purdue University focused on drug design for new antibiotics.

Dr. Łukasz Jaremko

Molecular Diagnostics and Drug Discovery (MD3) Group, Smart-Health Initiative (SHI), Red Sea Research Center (RSRC), Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Kingdom of Saudi Arabia

DETAILS
Talk
Elevated protein dynamics and druggability
Bio
Research in Professor Łukasz Jaremko's Molecular Diagnostics and Drug Discovery (MD3) group focuses on atomic-level insight into essential and topical questions from biochemistry and medicine, such as, e.g., the primary molecular bases of cancer, including leukaemia and lung cancer (Nature, 2021). The team is actively working in the field of targeted drug design and discovery, using structure-dynamics analysis to search for small molecules (ligands) that interact specifically with the disease-associated proteins. Identified lead compounds are then engineered to increase their binding and, thus therapeutic potency against cancer (Nature Chem Biol, 2021). Biomolecular nuclear magnetic resonance (NMR) spectroscopy is the crucial experimental technique used and refined (J Chem Phys B, 2015; Angewandte Chem, 2016; J Biomol NMR, 2018, 2020) to tackle challenging macromolecular assemblies (Nature Chem Biol, 2013, 2021; Science, 2014; Nature Communications, 2016, 2017; Nucleic Acids Res, 2019; Am J Hum Genetics, 2019; Chemical Science, 2020; eLife, 2021; Nature 2021; Mol. Cell 2021). These NMR-based structural studies are then combined with molecular and enzymatic assays as well as other state-of-the-art biophysical techniques such as X-ray crystallography, electron microscopy, circular dichroism and molecular dynamics simulations to get further insights into the complex biological systems essential for human health. Professor Łukasz Jaremko has published over 90 peer-reviewed papers in international journals covering original research of both methods development and application to address and monitor the pivotal biological, biomedical and environmental phenomena.

Registration

The registration fee includes attendance of all conference sessions, morning/afternoon coffee breaks and lunches, conference bag and program book.

Participation to the conference is considered final only once the registration fees have been paid. The number of participants is limited: once the number of paid registrations reaches the maximum number of participants, unpaid registrations will be cancelled.

Please note that, in order to finalize the scientific program in due time, at least one registration by anyone of the authors, denoted as Covering Author, is required to cover the presentation and publication of any accepted abstract. Covering Author registration deadline is 20 July 2022. Your abstract will be withdrawn if your registration is not complete by this date.

Authors with multiple contributions: Please note that one author registration will cover only ONE accepted contribution. Authors presenting more than 1 contribution during the event will be charged 25 euro per additional abstract (e.g., 1 author with 2 abstracts: registration fee + 25 euro; 2 authors with 3 abstracts: 2 registration fees + 25 euro; etc.)

Authors and reviewers of IJMS: Please note that the authors and reviewers of IJMS from the last 5 years will receive a 15% discount on the registration fees. This discount is not immediate, so you need to add the code AUT/REV-ISFMS2022 during your registration process. For any question or doubt, please send us an email to .

Certificate of Attendance: After the event, the participants of ISFMS2022 will be able to download an electronic Certificate of Attendance by log-in at their Sciforum personal account. Once you're logged-in, go to your profile and click on 'My certificates'. A list of all Sciforum events you've attended is available and you simply have to click on "Download" next to the correct event.

Conference Dinner: A Gala Dinner will be served on Friday, 9 September. Please note that the conference fee does not include this social event. Therefore, if you plan to attend the dinner, please make sure you select this extra when registering to the conference (Price per person: will be announced soon). Other social/networking events to be announced soon!

Early Regular Late Supported documents
Student 250.00 EUR 350.00 EUR 450.00 EUR Scanned copy or photograph of your current student ID is required.
Editorial Board Members/Guest Editors of IJMS 350.00 EUR 450.00 EUR 550.00 EUR
Post-Docs, PIs & Senior Scientists 450.00 EUR 550.00 EUR 650.00 EUR
Commercial 700.00 EUR 800.00 EUR 900.00 EUR
Waived Fees: Invited Speakers and MDPI Guests Free Free Free
Early fee valid until: 11/07/2022   Late fee valid from: 29/07/2022  

Cancellation policy

Cancellation of paid registration is possible under the terms listed below:

> 2 months before the conference

Full refund but 60 EUR are retained for administration

> 1 month before the conference

Refund 50% of the applying fees

> 2 weeks before the conference

Refund 25% of the applying fees

< 2 weeks before the conference

No refund

Disclaimer
In the unlikely event that MDPI shall deem it necessary to cancel the conference, all pre-paid registration fees will be reimbursed. MDPI shall not be liable for reimbursing the cost of travel or accommodation arrangements made by individual delegates.

Photographs and/or video will be taken during the conference
By taking part in this event you grant the event organizers full rights to use the images resulting from the photography/video filming, and any reproductions or adaptations of the images for fundraising, publicity or other purposes to help achieve the conference’s aims. This might include (but is not limited to), the right to use them in their printed and online publicity, social media, press releases and funding applications.

Payment methods

Wire transfer, Credit card


Instructions for Authors

Instructions

The "4th ISFMS — Biochemistry, Molecular Biology and Druggability of Proteins" will accept abstracts only.

The accepted abstracts will be available online on Sciforum.net during and after the conference. Moreover, participants will have the opportunity to contribute with a full manuscript to the special issue "Biochemistry, Molecular Biology and Druggability of Proteins" in the journal IJMS.

To present your research at the event

  • Create an account on Sciforum if you do not have one, then click on ‘New Submission’ on the upper-right corner of the window, or by clicking on ‘Submit Abstract’ at the top of this webpage.
  • Indicate what thematic area is best suited for your research.
  • Submit an abstract in English - the word limits are: minimum 150 words and maximum 300 words.
  • The deadline to submit your abstract is 24 June 2022. You will be notified by 1 July 2022 about the acceptance for poster presentation.
  • Upon submission, you can select if you wish to also be considered for oral presentation. Following assessment by the Chairs, you will be notified by 1 July 2022 in a separate email whether your contribution has been accepted for oral presentation.
  • Please note that, in order to finalize the scientific program in due time, at least one registration by any of the authors, denoted as Covering Author, is required to cover the presentation and publication of any accepted abstract. Covering Author registration deadline is 20 July 2022. Your abstract will be withdrawn if your registration is not complete by this date.

Poster Information

Maximum poster size limited to 90 × 140cm, vertical orientation preferred. Please print your poster prior to the conference.
A plan of the poster session will be circulated later on.

Publication Opportunities

  • All accepted abstracts will be available online in Open Access form on Sciforum.net.
  • Participants of this conference are cordially invited to contribute with a full manuscript to our Special Issue "Biochemistry, Molecular Biology and Druggability of Proteins" in the journal IJMS.
  • The submission deadline for this special issue is 28 February 2023. Conference participants will be granted a 15% discount on the publication fees. Please note that no other institutional discounts will be applicable, except from reviewers’ discount vouchers.
  • IJMS is indexed by the Science Citation Index Expanded (Web of Science), MEDLINE (PubMed), and other databases, and has an Impact Factor of 5.923 (2020).

Venue, Travel and Accommodation

Florence

Florence is a city in central Italy and the capital of the Tuscany region. During the Middle Ages, Florence was a centre of European trade and finance, and one of the wealthiest cities of that era.

The city attracts millions of tourists each year, and UNESCO declared the Historic Center of Florence a World Heritage Site in 1982. The city is noted for its culture, Renaissance art and architecture and monuments. The city also boasts numerous museums and art galleries, such as the Uffizi Gallery and the Palazzo Pitti, and still influences the fields of art, culture and politics to this day. Due to Florence's artistic and architectural heritage, Forbes has ranked it as one of the most beautiful cities in the world.

For more information visit http://www.firenzeturismo.it/en/.

Venue

The conference will take place in the biomedical campus of University of Florence, Viale G. Morgagni.


Best way to travel here

Florence may be reached directly by plane. The airport has connections with many of the main transport hubs in Europe (Rome, Milan, Paris, Frankfurt, Munich, Zurich) and a tram service connects the airport to the city centre. By train, it is a 90-minute trip from Rome or Milan where the largest airports in Italy are located. Pisa airport is just one hour from Florence by train and there are many flights into this city too.

The biomedical campus is 15 min by tram (T1) from the main train station which is in the city centre. Florence is a relatively small city (around 300 000 residents) and the public transportation (trams, trains, buses) is efficient and inexpensive.

Accommodation

There are huge numbers of tourists visiting Florence and Tuscany each year, in every season. For this reason, the accommodation should be booked in advance. There is a large number of hotels, B&Bs, Airbnbs or apartments which can be booked online by using booking.com or similar services. The best location to choose would be around the Santa Maria Novella train station or city centre, where the journey to the conference site will take roughly 15 minutes.

Beware of Unauthorized Registration and Hotel Solicitations
Note that Sciforum is the only official registration platform to register to ISFMS2022, and that we are not associated with any hotel agency. While other hotel resellers and travel agencies may contact you with offers for your trip, they are not endorsed by or affiliated with ISFMS2022 or Sciforum. Beware that entering into financial agreements with non-endorsed companies can have costly consequences.

Event Awards

The Sponsor, IJMS, offers two Best Posters Awards and one Best Oral Presentation award to our conference participants, which will be announced during the Award Ceremony on the last day of the conference.

The Awards
Best Poster Award (300€)
The two Best Posters will be selected by all conference attendees through secret vote.
Best Oral Presentation Award (500€)
The Best Oral Presentation will be selected by the Scientific Committee after evaluation of all selected talks presented during the conference

Sponsors and Partners

Sponsors and Partners


Sponsoring opportunities
If you are interested in knowing the sponsorship options for ISFMS2022 please look at our Sponsorship form.

For sponsorship and exhibition opportunities, please do not hesitate to contact us for more information.

Organizers


Sponsors


Media Partners

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